Dementia: from prevention to person-centred care

About this collection

This collection brings together Medpresso materials on dementia in older adults in a suggested order: an IAGG lecture on modifiable risk factors and multidomain prevention, a review of the biological mechanisms behind preventive interventions, two guidelines on diagnosing Alzheimer’s disease and Lewy body dementia, and a closing IAGG lecture on person-centred care for people living with dementia. It is meant for geriatricians, neurologists, psychiatrists, family physicians and everyone who cares for older adults.

Learning path

Follow the materials in order or open any item directly. The note under each title explains what it adds to the path.

  1. Prevention and reduction of cognitive decline (Lecture · 20 min · $20)
    Start here: Prof. Mohamed Khater outlines the growing burden of mild cognitive impairment and dementia and the modifiable risk factors behind it, from hearing loss and hypertension to diabetes and social isolation. He also presents the FINGER multidomain approach and how memory clinics can turn prevention into personalised plans.
  2. Can the trajectory of neurodegeneration be changed? Biological mechanisms of dementia prevention and the potential of personalised intervention (Article review · Free)
    The mechanisms behind prevention: a review of a 2025 paper in Molecular Neurodegeneration shows which biomarkers change with exercise, cognitive training, diet, blood pressure and glucose control, sleep and multidomain programmes such as FINGER, and why a better biomarker is not yet proof that dementia has been prevented.
  3. Diagnostic guidelines for Alzheimer's disease: 2024 revised criteria (Guideline · Free)
    From prevention to diagnosis: the Alzheimer’s Association 2024 revised criteria define Alzheimer’s disease by its biology. One abnormal Core 1 biomarker, including a plasma test with at least 90% accuracy, is enough for the diagnosis, while Core 2 biomarkers and the combined biological (A–D) and clinical (0–6) stages guide staging and prognosis, and clinical judgement still weighs copathology.
  4. Diagnosing and managing Lewy body dementia: DLB Consortium 2017 criteria (Guideline · Free)
    Often missed or mistaken for Alzheimer’s disease: the DLB Consortium’s 2017 criteria for dementia with Lewy bodies set out the four core features (fluctuating cognition, recurrent visual hallucinations, REM sleep behaviour disorder and parkinsonism), the indicative biomarkers (DAT imaging, MIBG scintigraphy, polysomnography), when probable DLB can be diagnosed, and why antipsychotics should be avoided whenever possible.
  5. Person-Centred Care for Persons Living with Dementia (Lecture · 28 min · $30)
    The path closes with care: Prof. Rosette Farrugia-Bonello describes the move from a biomedical to a biopsychosocial model: knowing the person beyond the diagnosis, supporting choice, dignity and remaining abilities, using respectful language and involving the family.

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