Why Oral Mucosa Heals Better Than Skin?
Biomolecules Journal published an interesting study providing an extensive overview of wound healing in skin versus oral mucosa. The process of wound healing follows four partially overlapping phases, no matter of which type of tissue is that: hemostasis, inflammation, proliferation, and remodeling. Alteration of any phase surely results in certain changes, like delayed wound healing, hypertrophic scar and contractures formation. Authors provide a detailed comparison in the general tissue architecture. Skin and oral mucosa share many features, but also have numerous differences. For example, the oral epithelium is thicker and better perfused with blood vessels compared to skin. Other differences are related to the environmental factors that the tissues are exposed to. Skin is constantly faced to air, various temperatures and humidity, whereas oral mucosa mainly exposed to warm and wet environment. An overview of all comparative details between skin and oral wounds is provided further by the link.