Vaping cannabinoids

Delve into an article authored by authors from Oregon State University in the United States. Their research scrutinizes the chemistry of vape carrier solvents, flavoring substances, and the resulting byproducts. Additionally, they engage in a discussion surrounding the act of vaping cannabinoids, a process that encompasses activities ranging from heating dried cannabis to the extraction of cannabis using solvents, which are then mixed with carrier solvents and additives. Research indicates that the resulting exposures and potential toxicity implications vary significantly among these different activities.
An astonishing 85% of all vapers have reported using products containing THC, the primary psychoactive compound found in cannabis. Up to this day, researchers have documented approximately 120 distinct phytocannabinoids, though there may be others that remain undiscovered. These terpenophenolic compounds typically share a common mode of action, interacting with cannabinoid receptors to modulate neurotransmitter release within the brain. The two most well-recognized and widely promoted cannabinoids are cannabidiol (CBD) and tetrahydrocannabinol (THC). It is essential to underscore that synthetic cannabinoids are associated with a significantly higher rate of morbidity and mortality compared to their natural phytocannabinoid counterparts. As the production of synthetic cannabinoids continues to surge, reports of abuse and associated toxicity are on the rise. Alarmingly, despite known health risks and the increasing availability of cannabis, many individuals persist in abusing synthetic cannabinoids for various reasons. These include their lower cost in comparison to cannabis and their ability to evade detection during routine drug screenings.