The importance of skin microbiome in inflammatory acne

Nearly 85% of young people ages 12-24 experience at least minor acne (acne vulgaris), making it a highly prevalent inflammatory skin condition. Recent publications highlight not only a gut microbiome involvement in acne, but also interactions with a skin microbiome. Traditionally, antibiotics and isotretinoin are the main remedies used for this pathology. However, these topical and systemic medications give rise to cutaneous dysbiosis. So the main contemporary treatment objective in acne is not to effect C. acnes but rather to prevent or to treat dysbiosis. Such new understanding of acne pathophysiology has changed the direction in acne treatment. One novel therapeutic approach is a vaccination strategy through acne immunotherapy. Read more in the original article.