Skeletal muscle aging
We continue to review a Life Sciences journal article Biomarkers of aging and today are covering the topic of muscle aging. The importance of skeletal muscle can't be underestimated, as it is the largest tissue by mass in the body, functioning as a posture and movements regulator, participates in respiration and metabolism. Incase of injury, muscle has an ability to regenerate following by a full function recovery. According to the authors, this is mainly due to existence of muscle stem cells. Nonetheless, aging process is irreversible- muscle mass gradually decline after 40, followed by a loss of muscle function, known as age-related sarcopenia. Therefore, physiological changes include weakness, sarcopenia, paralysis and failure. Histological aging stages are atrophy, fibrosis, inflammation and denervation. Learn more about the imaging traits of muscle aging, cellular alterations and molecular changes in the original publication.