Cystitis - update on causes and treatment
One-third of women will have had a urinary tract infection by age 24 and one-half by age 32, making cyctitis a very common pathology. It is an infection of the lower urinary tract and is typically caused by a bacterial infection of the urinary bladder. Escherichia coli is an etiologic agent in 75-95% of cases, followed by Klebsiella. The incidence of simple cystitis in men is relatively low. Cystitis most often develops due to the colonization of the periurethral mucosa by bacteria and the ascension of such pathogens to the urinary bladder. Impairment of the immune system is the main risk factor to develop UTIs. The antibiotic therapy is a treatment of choice: nitrofurantoin 100 mg twice a day for 5 to 7 days, sulfamethoxazole-trimethoprim twice a day for 3 days, fosfomycin 3 gm as a single oral dose, pivmecillinam 400 mg twice a day for 5 to 7 days. Details in the original article.