Chlorhexidine in Dentistry: Pharmacology, Uses, and Adverse Effects

A total of 1100 publications were identified by authors from Ontario, Canada, out of which 67 were chosen to undertake a comprehensive review of the current applications of chlorhexidine (CHX) in the field of dentistry, focusing on its mechanism of action. The primary objective of this investigation was to shed light on the most efficacious protocols that yield optimal clinical outcomes while minimizing the occurrence of unfavorable drug reactions. Within the realm of dentistry, CHX products serve both therapeutic and prophylactic purposes, showcasing rapid antimicrobial and antifungal properties that remain potent even at minimal concentrations. Notably, CHX exhibits its impact on both aerobic and anaerobic bacteria, extending its reach to the DNA and RNA viruses. The recommended concentration of CHX mouthwash ranges between 0.12% and 0.2%, ensuring an application of 18 to 20 mg per usage. It is noteworthy that CHX mouthwash is highly recommended over gels due to its superior efficacy. The utilization of CHX has proven advantageous as an adjunct to oral health, particularly in the field of periodontics, and as a preventive measure. Furthermore, it has demonstrated significant aid in diverse oral surgical procedures, including its involvement in implantology and periodontology. For more detailed insights into specific recommendations concerning various pathologies, please refer to the provided link.