Effects of Citrus Fruit Juices on Inflammation and Immunity

Micronutrients play a crucial role in supporting immune function, and citrus fruit juice emerges as a particularly rich source of two such micronutrients: vitamin C and folate. The vitamin C content in orange juice is reported to be 31 mg per 100 g. Previous research has indicated that commercially available orange juice contains approximately 15% less vitamin C compared to home-made juice. The overall folate content in orange is documented as 32 μg per 100 g. Folate plays an essential role in the synthesis of RNA and DNA, and consequently, it is vital for cell division, protein synthesis, and tissue growth. The significance of folate in immune system functionality is not surprising, given its involvement in these critical cellular processes.
In addition to micronutrients, citrus fruit juices contain several polyphenolic flavonoid compounds that are relevant to immune system health. Beyond their effects in supporting immune function and managing inflammation, the bioactive compounds present in citrus fruit juices may exhibit direct anti-viral effects. These effects have been emphasized in the context of infections like coronavirus. Human trials have demonstrated that orange juice possesses anti-inflammatory properties. However, further exploration is needed to fully understand its effects on both innate and acquired immunity. The potential of citrus fruit juices to positively impact immune function goes beyond the provision of micronutrients, extending to the diverse bioactive compounds they contain.