Liposomal bupivacaine (EXPAREL) in anesthesia practice

Sara Kufin · CLINICAL topics

I've been using Exparel for thoracic epidurals and intercostal nerve blocks. The extended pain relief is beneficial, but I've also been cautious about its potential for CNS and cardiovascular toxicity. Following the recommended guidelines closely, like spacing out administration from other local anesthetics, has been crucial. Any tips on administration techniques or handling potential side effects?

Comments

Sara Kufin: I'd appreciate any article recommendations on toxicity research

Pavlo Miroshnichenko: Nice topic, I'm interested as well. It's been used in upper extremity recently with good results. But it might not be available in all countries or practices.... 🔒 https://www.jhandsurg.org/article/S0363-5023(21)00759-0/fulltext